“Nature Reviews Neurology” Review Article: Functional brain networks in the evaluation of patients with neurodegenerative disorders

San Francisco | March 28, 2023 – NysnoBio collaborator and MJFF grant co-PI, David Eidelberg, recently published a review of his journey of over 20 years toward creating an imaging modality that has the potential to transform diagnosis and treatment of patients with neurodegenerative conditions like Parkinson’s disease (PD), Multiple System Atrophy (MSA), Progressive Supranuclear Palsy (PSP), Alzheimer’s disease (AD), and Frontotemporal Dementia (FTD).


 

Functional brain network alterations associated with Parkinson's disease.

 

We can finally move from forcing patients into years of diagnostic confusion toward a neural network imaging test that can accurately predict specificity within overlapping neurodegenerative conditions.

 

Novel functional brain network induced by subthalamic gene therapy for Parkinson's disease.

 

Because the specific network pattern becomes more entrenched over time, we can look for reversal of the pattern upon therapeutic treatments—non-invasive, definitive and patient-specific. NysnoBio is proud to be working with Dr. Eidelberg to develop additional patterns that define specific subtypes of PD in our efforts to create a new paradigm to advance promising therapeutics.


Read the full article at Nature.

Details on the funded study at The Michael J. Fox Foundation for Parkinson’s Research: Neural Network Imaging Analysis in Parkinson’s Disease Associated with Parkin Mutation



Contact NysnoBio to get involved or learn more:
info@nysnobio.com



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From Illumina.com: Using whole-genome sequencing to study early-onset Parkinson’s disease